DNA Methylation

DNA Methylation

DNA Methylation

DNA methylation is a form of DNA modification through chemical changes. The changes can be added and removed without changing the original DNA sequence or the genetic blueprint code.

CpG Dinucleotides

DNA modification occurs through the addition of a methyl group to the DNA at CpG dinucleotdies. CpG dinucleotides are cytosines which follow a guanine. The majority of these CpG dinucleotides are found within regulatory sequences of DNA, such as promoters.

DNA Methylation Processes

DNA methylation normally occurs during development to turn off and on certain genes at certain times within the developing embryo.

DNA methylation is also involved in X-chromosome inactivation, imprinting and suppressing certain genes.

 

 

DNA Methylation

DNA Methylation

DNA methylation is a process of modifying DNA to alter gene expression, as well as chromatin packaging. Read more from the links to the left and above to learn more about this fascinating modification to DNA, DNA Methylation.

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